Milan, December 11: Inter have failed to get beyond the Champions League group stage for a second successive season after losing 2-1 at home to Barcelona, with Ansu Fati's late winner making him the youngest scorer in the competition's history.
The Serie A leaders needed to at least match Borussia Dortmund's result against Slavia Prague due to being level on seven points before the game, but the Germans emerged 2-1 victors to secure their progression as Inter were made to rue their own wasteful finishing.
After weathering an early Inter storm, a much-changed Barca went ahead through fringe forward Carles Perez, though their lead did not last – Romelu Lukaku blasting in from 20 yards.
Lukaku was otherwise wasteful in front of goal, however, missing a particularly fine opportunity early in the second period, before the visitors sealed Inter's fate late on through 17-year-old Fati, dropping the Italians into the Europa League.
17y 40d - Ansu Fati has become the youngest goalscorer in Champions League history, scoring for Barcelona tonight aged just 17 years and 40 days. Whippersnapper. #UCL #INTBAR pic.twitter.com/z8TRAsr9Z9— OptaJoe (@OptaJoe) 10 December 2019
A purposeful start from Inter saw Lukaku have a goal disallowed for offside, while the Belgian had a close-range effort crucially deflected over by Clement Lenglet.
Barca steadily gained a foothold, however, and capitalised on Inter's profligacy in the 23rd minute - Perez sweeping home after Diego Godin deflected Antoine Griezmann's incisive pass to the forward.
Lenglet inexplicably missed the target from 12 yards just past the half-hour mark and Inter made him pay on the stroke of half-time, Lukaku drilling home after excellent hold-up play by Lautaro Martinez on the edge of the box.
Lukaku should have got a second just after the hour mark but he lashed straight at Neto in a one-on-one opportunity.
Martinez thought he had grabbed a late victory to take Inter through, yet Lukaku had strayed offside just prior to his fellow striker prodding home.
And substitute Fati fired in a historic winner four minutes from time to destroy Inter's hope of joining them in the last 16, sending a low shot in off the left-hand post.
What does it mean? No second chances for Inter
Antonio Conte attempted to motivate his Inter players by highlighting there were "no second chances" - this was their last opportunity to prove they could translate their Serie A season to the Champions League.
However, they wasted so many clear-cut opportunities. Inter's elimination is by no means down to any Barca brilliance - they did not even have Lionel Messi in the squad. No, they are out because of their own mistakes.
Alena and Todibo impress in Barca's Italian job
It has been a difficult season for Carles Alena, with a lack of first-team football resulting in links with transfers to other clubs. Yet in San Siro he proved he is capable of impressing for Barca, creating a team-high four chances.
Jean-Clair Todibo was arguably the visitors' best player, though, showing fine ability on the ball and immense composure, despite this being only his third outing of the campaign.
Careless Lukaku costs Inter
Although he got the goal to secure parity before half-time, Lukaku was otherwise a massive disappointment.
His lack of composure when smashing at Neto in the second half was startling, while he spurned other chances and was the one who was crucially in an offside position for the late disallowed Martinez goal.
Inter return to Serie A action on Sunday (December 15) at Fiorentina, as they await to hear their Europa League opponents in Monday's draw. Barcelona, meanwhile, go to fourth-placed Real Sociedad on Saturday (December 14), ahead of next week's Clasico.