Aston Villa's aspirations for the Champions League were dashed after a 2-0 loss to Manchester United, where Emiliano Martinez was dismissed. Amad Diallo and Christian Eriksen scored at Old Trafford. Martinez received a red card late in the first half for fouling Rasmus Hojlund. Despite Newcastle United's defeat to Everton, Villa finished sixth, securing a Europa League spot.
United took control when Diallo headed in Bruno Fernandes' precise cross in the 76th minute. Eriksen, playing his final game for United, doubled the lead with a penalty. This victory concluded a disappointing domestic season for United, who ended up in 15th place. Villa's loss meant they missed out on the top five.

Martinez had an eventful start, making four saves within the first ten minutes and witnessing Diogo Dalot hit the post. However, he was sent off after clashing with Hojlund due to Matty Cash's poor back pass. This marked him as the first Villa goalkeeper to receive a Premier League red card since Brad Friedel in 2009.
Before this match, only Jordan Pickford had more yellow cards without being sent off than Martinez among Premier League goalkeepers. Martinez became notable for making five saves and receiving a red card in one half since Opta began tracking such data in 2003-04. Villa's defeat was their second in their last ten league matches, both occurring in Manchester.
United continued their dominance after halftime, with Casemiro hitting the post and Morgan Rogers having a goal disallowed by referee Thomas Bramall. Diallo then scored from Fernandes' cross and won a penalty after being fouled by Ian Maatsen, which Eriksen converted to secure the win.
Bruno Fernandes provided his tenth Premier League assist of the season, marking his second campaign achieving double-digit assists (12 in 2020-21). He joins an elite group of Manchester United players who have assisted 10 or more goals in multiple seasons, including Eric Cantona, David Beckham, Ryan Giggs, Wayne Rooney, and Nani.
This match highlighted key performances and statistics that shaped both teams' seasons. While United celebrated individual achievements like Fernandes', Villa reflected on missed opportunities and disciplinary challenges that impacted their campaign outcome.