Houston Astros vs Chicago White Sox Injury Report MLB 2025: Head-to-Head Results, Where to Watch and More!

Houston Astros vs Chicago White Sox Injury Report MLB 2025: The Houston Astros and Chicago White Sox are set to face off on Saturday, May 3, 2025, at 2:10 PM EDT at Guaranteed Rate Field in Chicago.

This matchup comes amid significant injury challenges for both teams, affecting their lineups and pitching rotations. The Astros are anticipating the return of Lance McCullers Jr., who is slated to start on May 4. Meanwhile, the White Sox are dealing with recent injuries, including infielder Gage Workman.

Both teams have had to adjust their rosters due to a series of injuries. The Astros' pitching staff has been impacted by multiple injuries, including those to Forrest Whitley and Shawn Dubin, who are both on the 15-day injured list.

The White Sox are also managing injuries to key players such as Josh Rojas and Korey Lee, who are working their way back from toe and ankle injuries, respectively. As both teams navigate these challenges, depth and adaptability will be crucial in this midseason matchup.

Astros vs White Sox Game Information & How to Watch

Date: Saturday, May 3, 2025
Time: 2:10 p.m. ET
Location: Guaranteed Rate Field, Chicago, Illinois
TV: CHSN (White Sox broadcast), SCHN (Astros broadcast)

Houston Astros Injury Report

Player	Injury	IL Date	Expected Return	Status
Lance McCullers Jr.	Right flexor tendon surgery	March 27 (15-day IL)	May 4	Set to return and start vs. White Sox on May 4; first action since 2022 WS.
Forrest Whitley	Left knee sprain	April 27 (15-day IL)	TBD	Threw on April 30 without issues after re-aggravating Spring Training injury.
Shawn Dubin	Right shoulder inflammation	March 27 (15-day IL)	TBD	Threw 1 scoreless inning in Triple-A rehab on April 29.
Spencer Arrighetti	Broken right thumb	April 8 (15-day IL)	Mid-May	Thumb healing well after being hit during BP on April 7.
Taylor Trammell	Right calf strain	March 27 (10-day IL)	TBD	Doing baseball drills in West Palm Beach.
Luis Garcia	Tommy John surgery	April 7 (60-day IL)	TBD	Shut down with elbow inflammation, moved to 60-day IL.
Cristian Javier	Tommy John surgery	March 27 (15-day IL)	Midseason 2025	Underwent surgery on June 6; targeting post-All-Star break return.
J.P. France	Torn right shoulder capsule	March 27 (15-day IL)	Late 2025	Had surgery on July 1; expected recovery time 12–14 months.
Pedro León	Grade 1 MCL strain	March 27 (10-day IL)	Early 2025	Resumed running and drills after injury on Feb. 22.

Chicago White Sox Injury Report

Player	Injury	IL Date	Expected Return	Status
Gage Workman	Right hip flexor strain	(10-day IL)	Mid-May	Hurt himself fielding in the first inning on May 1.
Josh Rojas	Hairline fracture in right big toe	March 27 (10-day IL)	Week of May 4	Began rehab with Triple-A Charlotte on April 29.
Korey Lee	Left ankle sprain	April 10 (10-day IL)	TBD	Ankle swelling almost gone as of April 22.
Martín Pérez	Left elbow inflammation	April 19 (60-day IL)	TBD	Under evaluation following MRI on April 19.
Austin Slater	Right knee meniscus tear	April 12 (10-day IL)	Mid-to-late May	Had surgery on April 15 to repair meniscus.
Bryan Ramos	Right elbow strain	March 27 (10-day IL)	TBD	Reinstated April 11; optioned to Triple-A.
Mike Tauchman	Right hamstring strain	April 10 (10-day IL)	TBD	Injured rounding third on April 9; still under evaluation.
Mason Adams	Right elbow flexor strain	April 2 (Tommy John surgery)	2026	Underwent successful surgery on April 2.
Drew Thorpe	Tommy John surgery	March 27 (60-day IL)	2026	Will undergo surgery soon per team.
Prelander Berroa	Grade 1 right elbow strain	March 23 (60-day IL)	2026	Tommy John surgery announced March 7.
Ky Bush	Tommy John surgery	Feb. 17 (60-day IL)	2026	Surgery performed Feb. 12

Astros vs White Sox: Last 5 Head-to-Head Results

Date	Winner	Score
May 2, 2025	Chicago White Sox	White Sox 7–3
Aug 18, 2024	Houston Astros	Astros 2–0
Aug 17, 2024	Houston Astros	Astros 6–1
Aug 16, 2024	Chicago White Sox	White Sox 5–4
June 20, 2024	Houston Astros	Astros 5–3

In their last five meetings, the Houston Astros have secured three victories against the Chicago White Sox, showcasing a competitive edge in the series. The White Sox managed to clinch two wins, indicating a closely contested rivalry.

How to Stream Astros vs White Sox Online & Broadcast

To catch the Astros vs White Sox game live:

TV: CHSN (White Sox broadcast), SCHN (Astros broadcast)

With both teams battling for dominance in their divisions, this matchup holds substantial weight. Astros' standout José Altuve continues to impress, while the White Sox will rely on their depth to challenge Houston. Expect a competitive game on Saturday afternoon at Guaranteed Rate Field.