Houston Astros vs Chicago White Sox Live Stream, MLB 2025: The Houston Astros are set to face the Chicago White Sox on Saturday, May 3, 2025, at 2:10 p.m. ET at Guaranteed Rate Field in Chicago, Illinois.
This matchup features two teams at different points in their seasons: the Astros, aiming to solidify their position in the American League West, and the White Sox, looking to build momentum under new manager Will Venable.

The game will be broadcast on CHSN for White Sox fans and SCHN for Astros supporters, with live streaming available through Fubo. The Astros are coming off a loss in the series opener and will be looking to bounce back against a White Sox team that has shown flashes of potential despite a challenging start to the season.
With both teams dealing with injuries to key players, depth and adaptability will be crucial in this contest. Fans can expect a competitive game as both squads vie for a much-needed win.
| Time Zone | Offset | Local Time (May 3, 2025) |
|---|---|---|
| Pacific Time (PDT) | UTC -7 | 11:10 AM |
| Mountain Time (MDT) | UTC -6 | 12:10 PM |
| Central Time (CDT) | UTC -5 | 1:10 PM |
| Eastern Time (EDT) | UTC -4 | 2:10 PM |
| Argentina, Chile, Brazil | UTC -3 | 3:10 PM |
| Greenwich Mean Time (GMT) | UTC 0 | 6:10 PM |
| Central European Time | UTC +1 | 7:10 PM |
| Indian Standard Time | UTC +5:30 | 11:40 PM |
| Date | Winner | Score |
|---|---|---|
| May 2, 2025 | Chicago White Sox | White Sox 7–3 |
| Aug 18, 2024 | Houston Astros | Astros 2–0 |
| Aug 17, 2024 | Houston Astros | Astros 6–1 |
| Aug 16, 2024 | Chicago White Sox | White Sox 5–4 |
| June 20, 2024 | Houston Astros | Astros 5–3 |
In their last five meetings, the Houston Astros have secured three victories against the Chicago White Sox, showcasing a competitive series. The White Sox managed to clinch two wins, including the recent 7–3 victory on May 2, 2025. Overall, the Astros have demonstrated consistent performance in recent matchups.
| Player | Injury | IL Date | Expected Return | Status |
|---|---|---|---|---|
| Lance McCullers Jr. | Right flexor tendon surgery | March 27 (15-day IL) | May 4 | Set to return and start vs. White Sox on May 4; first action since 2022 WS. |
| Forrest Whitley | Left knee sprain | April 27 (15-day IL) | TBD | Threw on April 30 without issues after re-aggravating Spring Training injury. |
| Shawn Dubin | Right shoulder inflammation | March 27 (15-day IL) | TBD | Threw 1 scoreless inning in Triple-A rehab on April 29. |
| Spencer Arrighetti | Broken right thumb | April 8 (15-day IL) | Mid-May | Thumb healing well after being hit during BP on April 7. |
| Taylor Trammell | Right calf strain | March 27 (10-day IL) | TBD | Doing baseball drills in West Palm Beach. |
| Luis Garcia | Tommy John surgery | April 7 (60-day IL) | TBD | Shut down with elbow inflammation, moved to 60-day IL. |
| Cristian Javier | Tommy John surgery | March 27 (15-day IL) | Midseason 2025 | Underwent surgery on June 6; targeting post-All-Star break return. |
| J.P. France | Torn right shoulder capsule | March 27 (15-day IL) | Late 2025 | Had surgery on July 1; expected recovery time 12–14 months. |
| Pedro León | Grade 1 MCL strain | March 27 (10-day IL) | Early 2025 | Resumed running and drills after injury on Feb. 22. |
| Player | Injury | IL Date | Expected Return | Status |
|---|---|---|---|---|
| Gage Workman | Right hip flexor strain | (10-day IL) | Mid-May | Hurt himself fielding in the first inning on May 1. |
| Josh Rojas | Hairline fracture in right big toe | March 27 (10-day IL) | Week of May 4 | Began rehab with Triple-A Charlotte on April 29. |
| Korey Lee | Left ankle sprain | April 10 (10-day IL) | TBD | Ankle swelling almost gone as of April 22. |
| Martín Pérez | Left elbow inflammation | April 19 (60-day IL) | TBD | Under evaluation following MRI on April 19. |
| Austin Slater | Right knee meniscus tear | April 12 (10-day IL) | Mid-to-late May | Had surgery on April 15 to repair meniscus. |
| Bryan Ramos | Right elbow strain | March 27 (10-day IL) | TBD | Reinstated April 11; optioned to Triple-A. |
| Mike Tauchman | Right hamstring strain | April 10 (10-day IL) | TBD | Injured rounding third on April 9; still under evaluation. |
| Mason Adams | Right elbow flexor strain | April 2 (Tommy John surgery) | 2026 | Underwent successful surgery on April 2. |
| Drew Thorpe | Tommy John surgery | March 27 (60-day IL) | 2026 | Will undergo surgery soon per team. |
| Prelander Berroa | Grade 1 right elbow strain | March 23 (60-day IL) | 2026 | Tommy John surgery announced March 7. |
| Ky Bush | Tommy John surgery | Feb. 17 (60-day IL) | 2026 | Surgery performed Feb. 12 |
To catch the Astros vs White Sox game live:
With both teams striving for improvement in their divisions, this matchup holds significant importance. The White Sox will rely on their depth to challenge Houston. Expect a competitive game on Saturday afternoon at Guaranteed Rate Field.