The Arizona Diamondbacks and Chicago Cubs will meet on Sunday, March 30, 2025 at 4:10 p.m ET, for the final game of their four-game series at Chase Field in Phoenix, Arizona. This matchup features two teams looking to gain momentum early in the season.

Arizona, favored at -117 on the moneyline, will send Eduardo Rodriguez to the mound, while Chicago counters with Matthew Boyd. With both teams dealing with injuries and looking to shake off a rough start, this game presents a pivotal opportunity for both sides to get on track. Here's what you need to know about the odds, tips, and betting trends for the game.

Betting Odds and Key Insights
The Diamondbacks are slight favorites with a moneyline of -117, while the Cubs are priced at +106. Arizona is also favored on the run line at -1.5 (+162), with the Cubs at +1.5 (-202). The over/under is set at 9 total runs. Based on the moneyline, Arizona has a 53.9% implied chance to win, while the Cubs' chances sit at 46.1%.

Arizona's Strengths

Arizona boasts one of the best offenses in MLB, ranking first in batting average (.263) and second in slugging percentage (.440) last season. They are a dangerous team against left-handed pitchers, finishing with the second-highest wRC+ (119) and wOBA (.343) against them.

The Diamondbacks' pitching is strong, especially with Eduardo Rodriguez, who is hoping to bounce back after a rough 2024. His spring training results were promising, with increased velocity and a high strikeout rate.

Chicago's Challenges
The Cubs had a solid 2024 but are underdogs in this matchup. Their offense ranked 12th in runs per game but struggled against left-handed pitchers, sitting 16th in both wOBA (.307) and wRC+ (99). Matthew Boyd, who finished with a strong 2.72 ERA in a small sample last season, will look to keep the Cubs in the game. However, his injury history and inconsistency raise concerns.

Betting Trends
Arizona has a strong record as a favorite, winning 60.9% of the time in 2024. The Cubs, on the other hand, had a 47.5% win rate as underdogs. Arizona has dominated recent matchups, winning 13 of the last 20 games against Chicago. The total for the game has hit the over in 94 of Arizona's 162 games last season, suggesting a higher-scoring affair could be likely.

Read More: MLB 2025: Full Schedule, Start Times, and How to Watch (March 30, 2025)

Given the Diamondbacks' offensive power and home-field advantage, they are the pick to win. Consider betting on Arizona's moneyline (-117) and possibly the over on total runs.