Seebohm made her international debut in 2007, representing Australia. She has been associated with Griffith University in Australia and is coached by Michael Bohl. Over the years, she has earned numerous accolades, including the 2015 Female Australian Swimmer of the Year award, which she shared with Bronte Campbell. In 2017, she won the award outright.

| Season | Event | Rank |
|---|---|---|
| 2021 | Women's 4 x 100m Medley Relay | G Gold |
| 2021 | Women's 200m Backstroke | B Bronze |
| 2021 | Women's 100m Backstroke | 5 |
| 2016 | Women's 4 x 100m Medley Relay | S Silver |
| 2016 | Women's 100m Backstroke | 7 |
| 2016 | Women's 200m Backstroke | 12 |
| 2012 | Women's 4 x 100m Freestyle Relay | G Gold |
| 2012 | Women's 100m Backstroke | S Silver |
| 2012 | Women's 4 x 100m Medley Relay | S Silver |
| 2008 | Women's 4 x 100m Medley Relay | G Gold |
| 2008 | Women's 100m Backstroke | 9 |
Throughout her career, Seebohm faced several challenges. In 2019, she suffered from food poisoning during the Champions Swim Series in Guangzhou, China. She also underwent surgery for endometriosis in December 2016 after experiencing symptoms since 2011. Additionally, she dislocated her knee while riding a horse in May 2015 and collapsed due to swine flu during the 2011 Australian Championships.
In December 2020, Seebohm revealed her battle with an eating disorder. She shared that she had been dealing with this issue for over two years, involving bingeing, purging, and taking laxatives. Her openness about this struggle highlighted the pressures athletes face regarding body image and performance.
Seebohm comes from a family with a rich sporting background. Her father, John Seebohm, played over 300 games of Australian rules football for Glenelg in the South Australian National Football League. Her mother was a netball player and swimming coach. Her cousin Shannon Seebohm has played in Australia's National Basketball League and worked as a coach in Australia's Women's National Basketball League.
After failing to qualify for the 2019 World Championships in Gwangju, South Korea, Seebohm changed her coach and training base. She moved from Brisbane to the Gold Coast to train under Michael Bohl. This decision came after a period of self-reflection and disappointment over not making the team.
In 2019, Seebohm became an ambassador for Endometriosis Australia. She emphasised the importance of talking about the condition to raise awareness and help women understand what is normal regarding menstrual health.
Seebohm's contributions to swimming have been widely recognised. In February 2016, Brisbane City Council opened the Emily Seebohm Aquatic Centre in Fitzgibbon. She was also named the 2014 Short Course Swimmer of the Year by Swimming Australia and received the Medal of the Order of Australia (OAM) in 2009 for her services to sport.
Away from swimming, Seebohm enjoys spending time with horses, friends, and family. She also likes shopping and running. Her sporting idol is fellow Australian swimmer Ian Thorpe.
Seebohm has a unique pre-race ritual where she always puts her cap on from the back of her head to the front. Her sporting philosophy is simple yet profound: "Be the best you can be."
Emily Seebohm's journey is marked by early success, significant challenges, personal struggles, and advocacy for important causes. Her resilience and dedication continue to inspire many within and beyond the swimming community.Seebohm made her international debut in 2007, representing Australia. She has been associated with Griffith University in Australia and is coached by Michael Bohl. Over the years, she has earned numerous accolades, including the 2015 Female Australian Swimmer of the Year award, which she shared with Bronte Campbell. In 2017, she won the award outright.