Here is the list of all Most Sixes in ODI history:
| # | Player | 4s | 6s | Mat | Inn | Runs | HS | 100s | 50s | Avg |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Rohit Sharma India | 1090 | 357 | 282 | 274 | 11,577 | 264 | 33 | 61 | 48.85 |
| 2 | Shahid Afridi | 730 | 351 | 398 | 369 | 8,064 | 124 | 6 | 39 | 23.58 |
| 3 | Chris Gayle | 1128 | 331 | 301 | 294 | 10,480 | 215 | 25 | 54 | 37.83 |
| 4 | Sanath Jayasuriya Sri Lanka | 1500 | 270 | 445 | 433 | 13,430 | 189 | 28 | 68 | 32.36 |
| 5 | MS Dhoni India | 826 | 229 | 350 | 297 | 10,773 | 183* | 10 | 73 | 50.58 |
| 6 | Eoin Morgan England | 654 | 220 | 248 | 230 | 7,701 | 148 | 14 | 47 | 39.29 |
| 7 | AB de Villiers South Africa | 840 | 204 | 228 | 218 | 9,577 | 176 | 25 | 53 | 53.5 |
| 8 | Brendon McCullum | 577 | 200 | 260 | 228 | 6,083 | 166 | 5 | 32 | 30.42 |
| 9 | Sachin Tendulkar India | 2016 | 195 | 463 | 452 | 18,426 | 200* | 49 | 96 | 44.83 |
| 10 | Sourav Ganguly India | 1122 | 190 | 311 | 300 | 11,363 | 183 | 22 | 72 | 41.02 |
| 11 | Martin Guptill New Zealand | 750 | 187 | 198 | 195 | 7,346 | 237* | 18 | 39 | 41.74 |
| 12 | Jos Buttler England | 444 | 184 | 199 | 171 | 5,515 | 162* | 11 | 29 | 39.11 |
| 13 | Virat Kohli India | 1376 | 168 | 311 | 299 | 14,797 | 183 | 54 | 77 | 58.72 |
| 14 | Ricky Ponting Australia | 1231 | 162 | 375 | 365 | 13,704 | 164 | 30 | 82 | 42.04 |
| 15 | Glenn Maxwell Australia | 382 | 155 | 149 | 136 | 3,990 | 201* | 4 | 23 | 33.81 |
| 16 | Yuvraj Singh India | 908 | 155 | 304 | 278 | 8,701 | 150 | 14 | 52 | 36.56 |
| 17 | Chris Cairns New Zealand | 345 | 153 | 215 | 193 | 4,950 | 115 | 4 | 26 | 29.46 |
| 18 | Paul Stirling Ireland | 643 | 149 | 170 | 162 | 6,005 | 177 | 14 | 32 | 37.77 |
| 19 | Adam Gilchrist Australia | 1162 | 149 | 287 | 279 | 9,619 | 172 | 16 | 55 | 35.89 |
| 20 | Ross Taylor New Zealand | 713 | 147 | 236 | 220 | 8,607 | 181* | 21 | 51 | 47.55 |
| 21 | David Miller South Africa | 342 | 144 | 178 | 154 | 4,611 | 139 | 7 | 24 | 42.3 |
| 22 | Inzamam-ul-Haq Pakistan | 971 | 144 | 378 | 350 | 11,739 | 137* | 10 | 83 | 39.53 |
| 23 | Jacques Kallis South Africa | 911 | 137 | 328 | 314 | 11,579 | 139 | 17 | 86 | 44.36 |
| 24 | Virender Sehwag India | 1132 | 136 | 251 | 245 | 8,273 | 219 | 15 | 38 | 35.06 |
| 25 | Kieron Pollard West Indies | 171 | 135 | 123 | 113 | 2,706 | 119 | 3 | 13 | 26.02 |
| 26 | Quinton de Kock South Africa | 801 | 134 | 161 | 161 | 7,123 | 178 | 23 | 32 | 46.56 |
| 27 | Brian Lara | 1035 | 133 | 299 | 289 | 10,405 | 169 | 19 | 63 | 40.49 |
| 28 | Shane Watson Australia | 570 | 131 | 190 | 169 | 5,757 | 185* | 9 | 33 | 40.54 |
| 29 | David Warner Australia | 733 | 130 | 161 | 159 | 6,932 | 179 | 22 | 33 | 45.31 |
| 30 | Aaron Finch Australia | 532 | 129 | 146 | 142 | 5,406 | 153 | 17 | 30 | 38.89 |
| 31 | Herschelle Gibbs South Africa | 930 | 128 | 248 | 240 | 8,094 | 175 | 21 | 37 | 36.13 |
| 32 | Vivian Richards West Indies | 600 | 126 | 187 | 167 | 6,721 | 189* | 11 | 45 | 47 |
| 33 | Abdul Razzaq Pakistan | 382 | 124 | 265 | 228 | 5,080 | 112 | 3 | 23 | 29.71 |
| 34 | Wasim Akram | 247 | 121 | 356 | 280 | 3,717 | 86 | 0 | 6 | 16.52 |
| 35 | Shai Hope West Indies | 487 | 120 | 148 | 143 | 6,113 | 170 | 19 | 30 | 50.52 |
| 36 | Mohammad Nabi Afghanistan | 245 | 120 | 176 | 154 | 3,762 | 136 | 2 | 18 | 27.66 |
| 37 | Suresh Raina India | 476 | 120 | 226 | 194 | 5,615 | 116* | 5 | 36 | 35.31 |
| 38 | Marlon Samuels West Indies | 526 | 118 | 207 | 196 | 5,606 | 133* | 10 | 30 | 32.98 |
| 39 | Shoaib Malik Pakistan | 603 | 113 | 287 | 258 | 7,534 | 143 | 9 | 44 | 34.56 |
| 40 | Mohammad Hafeez Pakistan | 664 | 110 | 218 | 216 | 6,614 | 140* | 11 | 38 | 32.91 |
| 41 | Ben Stokes England | 282 | 109 | 114 | 99 | 3,463 | 182 | 5 | 24 | 41.23 |
| 42 | Mahmudullah Bangladesh | 425 | 107 | 239 | 209 | 5,689 | 128* | 4 | 32 | 36.47 |
| 43 | Sikandar Raza Zimbabwe | 373 | 106 | 153 | 144 | 4,476 | 141 | 7 | 24 | 36.99 |
| 44 | Elton Chigumbura Zimbabwe | 343 | 106 | 213 | 198 | 4,340 | 117 | 2 | 19 | 25.23 |
| 45 | Brendan Taylor Zimbabwe | 599 | 106 | 207 | 205 | 6,704 | 145* | 11 | 39 | 35.28 |
| 46 | Mitchell Marsh Australia | 285 | 103 | 99 | 95 | 3,098 | 177* | 4 | 20 | 37.33 |
| 47 | Andrew Symonds Australia | 449 | 103 | 198 | 161 | 5,088 | 156 | 6 | 30 | 39.75 |
| 48 | Tamim Iqbal Bangladesh | 925 | 103 | 243 | 240 | 8,357 | 158 | 14 | 56 | 36.65 |
| 49 | Aravinda De Silva | 711 | 102 | 308 | 296 | 9,284 | 145 | 11 | 64 | 34.9 |
| 50 | Mushfiqur Rahim Bangladesh | 617 | 100 | 274 | 256 | 7,795 | 144 | 9 | 49 | 36.43 |
| 51 | Saeed Anwar Pakistan | 938 | 97 | 247 | 244 | 8,824 | 194 | 20 | 43 | 39.22 |
| 52 | Hansie Cronje South Africa | 366 | 94 | 188 | 175 | 5,565 | 112 | 2 | 39 | 38.65 |
| 53 | Andrew Flintoff | 308 | 93 | 141 | 122 | 3,394 | 123 | 3 | 18 | 32.02 |
| 54 | Jonny Bairstow England | 437 | 92 | 107 | 98 | 3,868 | 141* | 11 | 17 | 42.98 |
| 55 | Angelo Mathews Sri Lanka | 468 | 90 | 226 | 195 | 5,916 | 139* | 3 | 40 | 40.24 |
| 56 | Mohammad Yousuf Pakistan | 785 | 90 | 288 | 273 | 9,720 | 141* | 15 | 64 | 41.72 |
| 57 | Kumar Sangakkara Sri Lanka | 1385 | 88 | 404 | 380 | 14,234 | 169 | 25 | 93 | 41.99 |
| 58 | Matthew Hayden Australia | 636 | 87 | 161 | 155 | 6,133 | 181* | 10 | 36 | 43.81 |
| 59 | Ijaz Ahmed snr Pakistan | 531 | 87 | 250 | 232 | 6,564 | 139* | 10 | 37 | 32.33 |
| 60 | Hamilton Masakadza Zimbabwe | 585 | 86 | 209 | 208 | 5,658 | 178* | 5 | 34 | 27.74 |
| 61 | Nathan Astle | 720 | 86 | 223 | 217 | 7,090 | 145* | 16 | 41 | 34.93 |
| 62 | Ajay Jadeja | 366 | 85 | 196 | 179 | 5,359 | 119 | 6 | 30 | 37.48 |
| 63 | Shivnarine Chanderpaul West Indies | 722 | 85 | 268 | 251 | 8,778 | 150 | 11 | 59 | 41.6 |
| 64 | Daren Sammy West Indies | 145 | 84 | 126 | 105 | 1,871 | 89 | 0 | 9 | 24.95 |
| 65 | Richie Berrington Scotland | 251 | 84 | 135 | 126 | 3,623 | 127 | 6 | 21 | 33.24 |
| 66 | Thisara Perera Sri Lanka | 176 | 84 | 166 | 133 | 2,338 | 140 | 1 | 10 | 19.98 |
| 67 | Kevin O'Brien Ireland | 332 | 84 | 153 | 141 | 3,619 | 142 | 2 | 18 | 29.42 |
| 68 | Craig McMillan | 373 | 84 | 197 | 183 | 4,707 | 117 | 3 | 28 | 28.19 |
| 69 | George Munsey Scotland | 271 | 83 | 72 | 70 | 2,642 | 191 | 3 | 18 | 44.03 |
| 70 | Fakhar Zaman Pakistan | 432 | 83 | 92 | 91 | 3,861 | 210* | 11 | 19 | 45.42 |
| 71 | Misbah-ul-Haq Pakistan | 342 | 83 | 162 | 149 | 5,122 | 96* | 0 | 42 | 43.41 |
| 72 | Mark Boucher South Africa | 356 | 83 | 295 | 221 | 4,686 | 147* | 1 | 26 | 28.57 |
| 73 | Muhammad Waseem United Arab Emirates | 141 | 81 | 65 | 65 | 1,698 | 119 | 1 | 9 | 26.12 |
| 74 | Jason Roy England | 511 | 81 | 116 | 110 | 4,271 | 180 | 12 | 21 | 39.92 |
| 75 | Jacob Oram | 182 | 81 | 160 | 116 | 2,434 | 101* | 1 | 13 | 24.1 |