The Ducati Team, however, won't go down without a fight - and especially not at Sepang. Andrea Dovizioso has a top record at the track and will be eager to bounce back from a tougher Australia. He was confirmed as second overall Down Under so that's less pressure in the rider standings, but the team spoils are important for him and team-mate Danilo Petrucci, and they've been ahead for some time.
Petrucci, after a crash at the start of the Australian GP, lost his record of being the only rider so far to have scored in every race too, and he'll want more for himself and the squad.
Quartararo in focus
The man he collided with at Phillip Island, Fabio Quartararo (Petronas Yamaha SRT), will also want a lot more from the weekend. After his FP1 crash saw him fighting to get back near the front on race day last time out, it's time to reset and try to impress in front of the home fans - not his, but the team's. Malaysia is Petronas turf and the quickest rookie on the block will be gunning for some big glory - as will his team-mate Franco Morbidelli, as he also had a tougher race last time out.
Quartararo is also up for top Independent Team rider honours and the Petronas Yamaha SRT outfit are fighting for top Independent Team, so there's plenty to play for.
Yamaha on the move
Phillip Island was also a tougher one for Monster Energy Yamaha MotoGP. Maverick Vinales was the fastest man all weekend - Marquez also said as much - but disaster struck just a few corners from the finish line as he battled the reigning champion. How will he feel heading into Malaysia? He knows, at least, he had the speed to challenge the number 93 in Australia, even if it didn't all come together at the end, and he's not too far behind Alex Rins (Team Suzuki Ecstar) in the fight for third overall.
Vinales' team-mate Valentino Rossi also had a tougher latter half of the race in Australia, although 'The Doctor' led the race in the initial stages and took a solid points finish in his 400th GP. But he's not about solid points finishes, so it's a bit of a bounce back on the cards for the number 46 - at least in terms of his pace throughout the whole race.
Miller stands up
Jack Miller is the man who stands to ruin the Petronas Yamaha SRT party for Quartararo in terms of the Independent Team rider standings, and the Aussie took a stunning home podium last time out as top Ducati. Can he reel in even more ground? And can Cal Crutchlow (LCR Honda Castrol) get back on the box?
The Briton was second Down Under to take his best finish of the season, and that at the track where he suffered his huge and potentially career-threatening crash last year. His is a longer shot at stopping the young hotshot Frenchman, but the maths say it's possible....